Stemolecule™ CHIR99021（GSK-3β抑制劑） 生化試劑
簡(jiǎn)要描述：
Stemolecule™ CHIR99021（GSK-3β抑制劑）：氨基嘧啶CHIR99021是目前為止報(bào)道的選擇性Z強(qiáng)的GSK-3β抑制劑。與其他強(qiáng)效的GSK-3抑制劑相比，CHIR99021不會(huì)交叉抑制細(xì)胞周期蛋白依賴性激酶（CDKs），對(duì)GSK-3β的選擇性是對(duì)CDKs的350倍。
產(chǎn)品時(shí)間：2023-02-15
打印當(dāng)前頁(yè)Stemolecule™ CHIR99021（GSK-3β抑制劑）
產(chǎn)品關(guān)鍵詞：
GSK-3β；na?ve stem cells 初始干細(xì)胞；neural progenitor cells 神經(jīng)祖細(xì)胞；WH-4-023；Y27632；PD0325901；CAS：252917-06-9；
產(chǎn)品描述：
氨基嘧啶CHIR99021是目前為止報(bào)道的選擇性zui強(qiáng)的GSK-3β抑制劑。與其他強(qiáng)效的GSK-3抑制劑相比，CHIR99021不會(huì)交叉抑制細(xì)胞周期蛋白依賴性激酶（CDKs），對(duì)GSK-3β的選擇性是對(duì)CDKs的350倍。與抑制MAPK來(lái)源的分化誘導(dǎo)信號(hào)聯(lián)合，使用CHIR99021阻斷 GSK-3β信號(hào)使得胚胎干細(xì)胞能自我更新。
產(chǎn)品特性
同義名：6-[[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2 pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
分子式：C22H18Cl2N8
分子量：465.34 g/mol
CAS NO：252917-06-9
純度：＞95%（HPLC）
外觀：Off-white solid
溶解性：DMSO
保存和穩(wěn)定性：粉末4 °C避光保存，重溶后的儲(chǔ)存液分裝后-20 °C保存，6個(gè)月穩(wěn)定。
質(zhì)量控制：HPLC測(cè)定純度，MS測(cè)定準(zhǔn)確分子量，CHIR99021對(duì)小鼠胚胎干細(xì)胞的細(xì)胞毒性測(cè)試。
結(jié)構(gòu)圖：
訂購(gòu)信息：原裝好貨，歡迎訂購(gòu)，：，：。
品牌 | 名稱 | 貨號(hào) | 規(guī)格 |
Stemgent | Stemolecule™ CHIR99021 | 04-0004 | 2 mg |
Stemgent | Stemolecule™ CHIR99021 | 04-0004-10 | 10 mg |
Stemgent | Stemolecule™ CHIR99021 | 04-0004-02 | 2 mg (10 mM) |
引用文獻(xiàn)：
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— —Written/Edited by V. Shallan【版權(quán)歸MKBio懋康所有】
上海懋康生物科技有限公司是一家涉足于生命科學(xué)和生物技術(shù)領(lǐng)域研究的試劑、儀器和實(shí)驗(yàn)室消耗品與實(shí)驗(yàn)服務(wù)工作，主要從事細(xì)胞生物學(xué)、植物學(xué)、分子生物學(xué)、免疫學(xué)、生物化學(xué)、蛋白組學(xué)。生物制藥與診斷試劑研發(fā)生產(chǎn)等領(lǐng)域。 本公司秉承“以人為本，以誠(chéng)為信、合同守信"的經(jīng)營(yíng)理念。堅(jiān)持"品質(zhì)保障"的原則為廣大客戶提供優(yōu)質(zhì)產(chǎn)品。
Stemolecule™ CHIR99021（GSK-3β抑制劑）
Stemolecule™ CHIR99021（GSK-3β抑制劑）
Stemolecule™ CHIR99021（GSK-3β抑制劑）